The National Safety Council has a grim prediction: 307 people will die in traffic accidents over the three-day Christmas holiday period.
And 346 will lose their lives over the three-day New Year's holiday period.
A combination of low gas prices, lower unemployment, and good driving weather means more people will be on the road, increasing the risk of fatal accidents.
Ken Kolosh manages the statistics group for the National Safety Council.
He says many of the deaths are preventable. Take the very simple act of buckling up in the car.